Diseases Caused by Air Pollution Has Been Emphasized Once (Know the Value of Your Nose!)


A study conducted at the University of Edinburgh in England concluded that nanoparticles in the air could enter the bloodstream and cause disease in people living in areas with air pollution. Inhaler nanoparticles pumped in vehicle exhausts, especially diesel vehicles, can travel to the lungs and bloodstream and increase the risk of heart attack and stroke. The most worrying point is that researchers at a London briefing have found nanoparticles to be a coronary people who suffer from heart disease tend to accumulate in damaged blood vessels and can make it worse. According to the World Health Organization, outdoor air pollution of both cities and rural areas is estimated to cause 3.0 million premature deaths worldwide in 2012.


Image source: Toxic air pollution nanoparticles ...
Until now, scientists were not sure how the particles entering the lungs affected their heart health. The new findings published on Wednesday in the ACS Nano Journal are based on earlier evidence and show that airborne particles in the air are in the blood and will be transported to many different parts of the body, including arteries, blood vessels and the heart.

Researchers have also analyzed surgically removed plaques from people at high risk of stroke and have discovered that nanoparticles tend to accumulate in greyish plaques that grow in the blood vessels and cause heart attacks and stroke. It was emphasized that these findings show the importance of reducing emissions and limiting the exposure of humans to nanoparticles.

Researchers have also analyzed surgically removed plaques from people at high risk of stroke and have discovered that nanoparticles tend to accumulate in greyish plaques that grow in the blood vessels and cause heart attacks and stroke. It was emphasized that these findings show the importance of reducing emissions and limiting the exposure of humans to nanoparticles.

Findings can help explain why air pollution increases heart disease and stroke risk. But what is really worrisome is that current legislation and efforts to regulate air pollution indicate that they focus on the wrong particles. While trying to prevent airborne scattering of large particles in the laws issued abroad in order to prevent air pollution, these include preventing nanoparticles from spreading after the combustion of diesel fuel products.

Many studies have shown that air pollution will result in millions of premature deaths each year. Even in Europe with relatively clean air, air pollution is blamed for 400,000 premature deaths annually. Most of these deaths are due to increased risk of cardiovascular disease: short exposure to high pollution can trigger heart attacks and strokes; prolonged exposure causes vascular damage. The big question is, we suspected that some of the nanoparticles that we breathed for a long time could interfere with blood circulation and damage blood vessels, but this has never been shown. These nanoparticles are mostly carbon compounds and it is extremely difficult to find them in our carbon-based life forms.

Particularly in this study, very small particles not covered by environmental pollution laws were investigated. How they proved and did it, the work team volunteered to breathe air full of harmless gold nanoparticles. Within 15 minutes, the nanoparticles began to appear in the blood of the volunteers and after three months they were still found in blood and urine. Team Leader Mark Miller commented: "Three months later we were really surprised that the gold nanoparticle levels were too high".

Gold nanoparticles are a product that is inert (does not enter any chemical reaction in the body); reactive compounds present in air pollution can have any harmful effect from clogging blood vessels to preventing clotting.

It can be said that working has come a long way in explaining why air pollution is causing vascular injuries and illness. If these findings with gold particles reflect the movement of carbon particles produced by exhaust, it is inevitable that the modern production of small particles with the modern engines will be a source of more concern. The next goal of the working team is to investigate whether gold nanoparticles enter the brain ... Air It has been found that brain diseases such as pollution, dementia, Alzheimer's and Parkinson's increase the risk, and in a recent study iron emulsions in human brain could come from vehicle exhausts.

Small Nanoparticles in the Air Difficult to Measure!

Air quality legislation in the European Union and elsewhere specifies a limit of 2.5 micrometres smaller than PM2.5 to measure the amount of particulate matter. However, the boundary is on the total mass of these particles, in a mere cubic meter of air rather than the total number. Thousands of ultra fine particles may have much less weight than relatively large ones. In recent years, PM 2.5 per cubic meter has fallen in rich countries, suggesting that air pollution is rising. However, as the number of diesel vehicles on the European road increases, the number of very fine particles increases during this period. Should air quality legislation change in Europe?

The problem is that it is very difficult to measure the number of very fine particles and it can not be done using widely used road-edge devices to track air pollution. The worker's statement emphasizes: "Ideally we want to measure numbers". "But the technology is not enough." The UK government now wants to postpone publishing its latest plan for fighting air pollution, a plan to produce after losing a set of cases brought by the ClientEarth.

ClientEarth investigators are warning about the violations of EU borders for gas nitrogen dioxide rather than particles. However, one of the measures to reduce nitrogen dioxide levels, "removing diesel vehicles from the road", can also help to reduce particle levels.

Importance of Our Nose in Polluted Air



Image source: The Nose: Hey, FWay
There are a total of 6 nasal turbinates in our nose (total 3 in each nasal cavity). These noses work like a unique machine that conveys, heats, moisturizes and pressurizes air when the outside air enters the nose. There is a mucus layer covering nasal flesh and a siliceous system that moves this mucus layer backward on the outermost epithelium surface. That is, when air is taken from our nose, our nose increases resistance to air, it keeps harmful particles, air is purged, heated and pressurized to the lung end airways. In the article "Your Nose, the Guardian of Your Lungs" of the American Academy of Nursing, emphasis was placed on healthy nose for lungs. Respiratory nanoparticles are responsible for pulmonary inflammation and depression due to particle size after inhalation. Specifically, people living in areas such as the People's Republic of China where there are dirty weather conditions need to wear masks and wash their regular noses with salt water. During nasal surgery, it is very important to minimize the volume of nasal turbinatesand to avoid the total or partial removal of the nasal turbinates. In the case of complete removal of nasal turbinates (empty nose syndrome) or a hole in the nasal septum, a very rapid decrease in nasal function may be seen as a result of increased airflow (hyperventilation) in the nasal air. Patients with nasal features in this way are more susceptible to air pollution and the risk of airborne nanoparticles spreading to the lungs and body is higher.

Source scientific study link:

Mark R. Miller*†∞∇ , Jennifer B. Raftis‡∞∇, Jeremy P. Langrish†, Steven G. McLean†, Pawitrabhorn Samutrtai§, Shea P. Connell†, Simon Wilson†, Alex T. Vesey†, Paul H. B. Fokkens∥, A. John F. Boere∥, Petra Krystek⊥, Colin J. Campbell§, Patrick W. F. Hadoke†, Ken Donaldson‡, Flemming R. Cassee∥#, David E. Newby†, Rodger Duffin‡∇, and Nicholas L. Mills

Inhaled Nanoparticles Accumulate at Sites of Vascular Disease


ACS Nano, 2017, 11 (5), pp 4542–4552
DOI: 10.1021/acsnano.6b08551
Publication Date (Web): April 26, 2017

http://pubs.acs.org/doi/abs/10.1021/acsnano.6b08551


Other resource links:

  • Pollution nanoparticles may enter your blood and cause disease

  • Standards - Air Quality - Environment - European Commission

  • Air legislation in Europe - European Environment Agency - Europa EU

  • Air Quality Legislation and Standards in the European Union ...

  • ClientEarth to sue Government over 'flawed' air pollution plan for third ...

  • https://www.newscientist.com/issue/3151/

  • Study finds how polluting nanoparticles get into blood and damage ...

  • Magnetite pollution nanoparticles in the human brain. - NCBI

  • WHO | WHO releases country estimates on air pollution exposure and ...

  • WHO Global Urban Ambient Air Pollution Database (update 2016)

  • Particle size dependent deposition and pulmonary ... - NCBI - NIH

  • Your Nose, the Guardian of Your Lungs | American Academy of ...

  • Atmospheric Nanoparticles and Their Impacts on Public Health ...

  • A perspective on the developmental toxicity of inhaled nanoparticles ...


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