Treatment of "PFAPA Syndrome" With Tonsillectomy and Adenoidectomy Operation

Tonsillectomy and Adenoidectomy Surgery is the Most Effective Method in the Treatment of PFAPA Syndrome!

PFAPA Syndrome (Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis)


PFAPA Syndrome (Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis)

PFAPA (periodic fever), aphthous stomatitis [aphthous stomatitis], pharyngitis [adenitis] syndrome is a clinical condition associated with tonsillitis in recent years (PFAPA Syndrome). - Symptoms, Diagnosis, Treatment). The characteristics of this clinical picture can be summarized as follows:

Oral wounds (aphthous stomatitis), exudates on the tonsils (white spots) and lymph node enlargements (lymphadenopathies) can be added to the table, which starts with throat redness and sore throat. Fever usually starts suddenly and lasts about 3-7 days. Sometimes the fever can last for several weeks. In some children, symptoms such as joint pain, abdominal pain, rash, headache, vomiting or diarrhea may also occur. Among the attacks, the children are completely in good condition.

The disease can last for several years, but usually disappears spontaneously in the second decade of life. In about 15% of patients, symptoms may persist during adulthood.

PFAPA syndrome is usually seen in children aged 2-5 years. There is no gender discrimination and can be seen in people of all ethnic backgrounds. You can see more detailed link about PFAPA Syndrome >> PFAPA Syndrome - Symptoms, Causes, Diagnosis, Treatment
Why does PFAPA syndrome occur?
The answer to this question is not yet known. Although this syndrome is sometimes found in more than one family member; no genetic disorder was detected. It is not an infectious disease. Although the symptoms are thought to be related to an inflammatory process during the episode; the cause of this clinical picture has not been fully reported.
How is PFAPA Diagnosed?
There is no specific diagnostic test for PFAPA. The disease is diagnosed based on physical examination findings and symptoms. White blood cell count, sedimentation rate, C - reactive protein can be measured by blood test and their value can be increased during the attack period. For the diagnosis, it is important to have a dramatic response to cortisone treatment after investigating the absence of a disease causing the present symptoms.
How is PFAPA syndrome treated?
In PFAPA Syndrome, administration of cortisone at the onset of an attack may typically lead to rapid resolution of symptoms, but may shorten the duration of the next attack.

Acetaminophen and ibuprofen drugs that can be given for fever during attacks are generally ineffective. A single dose of cortisone therapy (usually prednisone) can be used to resolve symptoms rapidly at the beginning and at the end of the attack. However, the interval between attacks may be shortened with this treatment and the next episode may come sooner.

It has been shown that if cimetidine and colchicine group drugs are used regularly, attacks are reduced in one third of children with PFAPA.
The most effective treatment for this syndrome is tonsillectomy. Tonsil surgery together with tonsil surgery to increase the success of treatment. The role and timing of surgery in PFAPA treatment is still not fully understood. However, the most effective treatment for this syndrome is reported.

PFAPA Syndrome What Are The Medical Branches Of Interest?

Patients with PFAPA syndrome should be evaluated by a pediatric rheumatologist and otolaryngologist. Pediatric Rheumatology Specialist, Prof. Dr. Özgür Kasapçapur (www.ozgurkasapcopur.com) for the evaluation, I refer to him.

The most effective medical treatment tool for the treatment of PFAPA syndrome is corticosteroids!

The most effective medical treatment tool of PFAPA syndrome is corticosteroids. However, this group of hormone drugs have negative effects such as having side effects, not eliminating the harvest precisely, causing the next attack to come sooner.

The most effective treatment tool in children with PFAPA syndrome is tonsillectomy!

Treatment of PFAPA Syndrome - Thermal Welding Device - Tonsillectomy

The most effective treatment tool in children with PFAPA syndrome is tonsillectomy. If the adenoidectomy operation is performed together with the tonsillectomy, the chances of success increase. I suggest you to read a comprehensive meta-analysis on the subject >>  PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment. In addition, in the following sources, you can also find detailed information about PFAPA.

Most of the children with PFAPA whom I have undergone tonsil surgery and adenoidectomy surgery were children aged 2-4 years. I performed all of them with tonsillectomy with Thermal Welding Method.

Source links >>

- Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome (PFAPA) (Juvenile)
- Periodic Fever Syndrome - Cleveland Clinic
- Pearls & Pitfalls - PFAPA: Recurrent Periodic Fever, Aphthous ...
- PFAPA syndrome in children evaluated for tonsillectomy ...
- Periodic fever, aphthous stomatitis, pharyngitis, and adenitis ...
- PFAPA Syndrome: Hereditary Periodic Fever ...

Murat Enoz, MD, Otorhinolaryngology, Head and Neck Surgeon - ENT Doctor in Istanbul

Private Office:
Address: İncirli Cad. No:41, Kat:4 (Dilek Patisserie Building), Postal code: 34147, Bakırköy - İstanbul
Appointment Phone: +90 212 561 00 52
E-Mail: muratenoz@gmail.com
Mobile phone: +90 533 6550199
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